Human Milk Oligosaccharides (HMO)

HMO are 3rd largest solid component of breastmilk - a complex mix of carbohydrates and bioactive compounds nurturing the immune system and microbiota in early infancy.

Symptoms

HMO in
Breastmilk

Supporting immune health in four major ways.1,2

HMO benefits in breastmilk: Eliminate pathogens through a decoy effect; Educate the developing immune system; Strengthen gut barrier function; and Nurture infant-type bifidobacteria.

HMO - Nurturing
the Immune
System and
Microbiota in
CMPA

Clinical Evidence Supporting
the HMO Blend3-5

Symptoms

Lowered frequency of
upper respiratory tract
infections.

Symptoms

Fewer parental reports of
bronchitis/lower respiratory track
infections

Symptoms

A microbiota closer to that of breastfed infants.

Clinical Trials Supporting our HMO Blend

Supplementation of 2'-FL and LNnT in our hypoallergenic specialty formula range

Confirmed hypoallergenicity of a novel whey based extensively hydrolyzed infant formula containing two human milk oligosaccharides.

Nowak-Wegrzyn A, et al. Nutrients. 2019;11:1447.

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Effects of an Extensively Hydrolyzed Formula Supplemented with Two Human Milk Oligosaccharides on Growth, Tolerability, Safety and Infection Risk in Infants with Cow’s Milk Protein Allergy: A Randomized, Multi-Center Trial.

Vandenplas Y et al. Nutrients 2022, 14, 53

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An Extensively Hydrolyzed Formula Supplemented with Two Human Milk Oligosaccharides Modifies the Fecal Microbiome and Metabolome in Infants with Cow’s Milk Protein Allergy.

Boulangé CL, Pedersen HK, Martin FP, Siegwald L, Pallejà Caro A, Eklund AC, Wei J, Zhang H, Berger B, Sprenger N, Heine RG and CINNAMON Study Investigator Group.. Int J Mol Sci 2023, 24, 11422.

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Baby smiling

Effects of an Amino Acid-Based Formula Supplemented with Two Human Milk Oligosaccharides on Growth, Tolerability, Safety, and Gut Microbiome in Infants with Cow’s Milk Protein Allergy.

Gold M.S, Quinn PJ, Campbell D.E, Peake J, Smart J, Robinson M, O’Sullivan M, Vogt J.K, Pedersen H.K, Liu X et al. Nutrients 2022, 14, 2297

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Tailored Solutions with
Immune Nurturing Benefits

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Althéra® HMO

Extensively hydrolyzed formula (eHF) for infants and young children with cow’s milk protein allergy (CMPA).
From birth onwards.

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Alfaré® HMO

Extensively hydrolyzed formula (eHF) for infants and young children with CMPA-related malabsorption.
From birth onwards.

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Alfamino® HMO

For infants and young children with severe forms of cow’s milk protein allergy (CMPA), multiple-food protein allergy (MFPA), those who fail on an eHF and for other conditions requiring an amino acid formula (AAF).
From birth onwards.

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Alfamino® Junior HMO

A young child formula for those with severe forms of cow’s milk protein allergy (CMPA), multiple-food protein allergy (MFPA), and for other conditions requiring an amino acid formula (AAF).
From 12 months to 13 years.

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